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Page 1
An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance.
Wu KJY, Tresco BIC, Ramkissoon A, Aleksandrova EV, Syroegin EA, See DNY, Liow P, Dittemore GA, Yu M, Testolin G, Mitcheltree MJ, Liu RY, Svetlov MS, Polikanov YS, Myers AG. Wu KJY, et al. Among authors: syroegin ea. Science. 2024 Feb 16;383(6684):721-726. doi: 10.1126/science.adk8013. Epub 2024 Feb 15. Science. 2024. PMID: 38359125
A synthetic antibiotic class overcoming bacterial multidrug resistance.
Mitcheltree MJ, Pisipati A, Syroegin EA, Silvestre KJ, Klepacki D, Mason JD, Terwilliger DW, Testolin G, Pote AR, Wu KJY, Ladley RP, Chatman K, Mankin AS, Polikanov YS, Myers AG. Mitcheltree MJ, et al. Among authors: syroegin ea. Nature. 2021 Nov;599(7885):507-512. doi: 10.1038/s41586-021-04045-6. Epub 2021 Oct 27. Nature. 2021. PMID: 34707295 Free PMC article.
Practical Synthesis of N-Formylmethionylated Peptidyl-tRNA Mimics.
Thaler J, Syroegin EA, Breuker K, Polikanov YS, Micura R. Thaler J, et al. Among authors: syroegin ea. ACS Chem Biol. 2023 Oct 20;18(10):2233-2239. doi: 10.1021/acschembio.3c00237. Epub 2023 Jul 11. ACS Chem Biol. 2023. PMID: 37433044 Free PMC article.
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion.
Aleksandrova EV, Wu KJY, Tresco BIC, Syroegin EA, Killeavy EE, Balasanyants SM, Svetlov MS, Gregory ST, Atkinson GC, Myers AG, Polikanov YS. Aleksandrova EV, et al. Among authors: syroegin ea. bioRxiv [Preprint]. 2023 Sep 28:2023.09.27.559749. doi: 10.1101/2023.09.27.559749. bioRxiv. 2023. PMID: 37808676 Free PMC article. Updated. Preprint.
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it.
Aleksandrova EV, Wu KJY, Tresco BIC, Syroegin EA, Killeavy EE, Balasanyants SM, Svetlov MS, Gregory ST, Atkinson GC, Myers AG, Polikanov YS. Aleksandrova EV, et al. Among authors: syroegin ea. Nat Chem Biol. 2024 Jan 18. doi: 10.1038/s41589-023-01525-w. Online ahead of print. Nat Chem Biol. 2024. PMID: 38238495
13 results